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Invited Talk,
Friday, 6.9., 9:00-10:00, Günter Hotz Lecture Hall

Extracting Quantitative Models in Molecular Biology

Gene Myers
Max Planck Institute for Molecular Cell Biology and Genetics

Slides

Rapid progress in understanding the molecular basis of life is being made now that we can image any genetic agent of interest with a light microscope, and to a lesser degree with electron microscopes. But building quantitatively accurate models from such data is very difficult due to limited resolution and limited signal to noise ratios. While much is being learned by human examination of such imagery, truly successful or even good software for this domain lags far behind what one might think in principle should be possible: the modeling of molecular mechanisms within the cell, modeling of the developmental trajectory of growing organs, and mapping the cellular anatomy of organisms and organs such as a fly brain. This talk is aimed at introducing the audience to this range of problems with examples from my group’s work, and illustrating what may be possible in the near future.